ESTROGEN, THROUGH ESTROGEN RECEPTOR 1, REGULATES HISTONE MODIFICATIONS AND CHROMATIN REMODELING DURING SPERMATOGENESIS IN ADULT RATS

Estrogen, through estrogen receptor 1, regulates histone modifications and chromatin remodeling during spermatogenesis in adult rats

Estrogen receptors (ESR1 and ESR2) play crucial roles in various processes during spermatogenesis.To elucidate individual roles of ESRs in male fertility, we developed in vivo selective ESR agonist administration models.Adult male rats treated with ESR1 and ESR2 agonist for 60 days show spermatogenic defects leading to reduced sperm counts and fert

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End-to-End Automated Lane-Change Maneuvering Considering Driving Style Using a Deep Deterministic Policy Gradient Algorithm

Changing lanes while driving requires coordinating the lateral and longitudinal controls of a vehicle, considering its running state and the surrounding environment.Although the existing rule-based automated lane-changing method is simple, it is unsuitable for unpredictable scenarios encountered in practice.Therefore, using a deep deterministic pol

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Postpartum Intrauterine Contraceptive Device (PPIUCD) Versus Interval Intrauterine Contraceptive Device (IUCD) Complications: Which is better?

Introduction: Intrauterine Contraceptive Device (IUCD) is an effective mode of contraception.But its timing of insertion remained debateable.Studies has shown that Postpartum Intrauterine Contraceptive Device (PPIUCD) is associated with less complications as compared to interval IUCD.But controversial results have been noted.This study aims to comp

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